How do I know if I have ochronosis?

This disease entity may be first noticed in newborns as their urine may be darker than normal. People are often without symptoms until later in life when the skin, sclera (white part of the eye), ears, and nose may develop pigmentary changes. Ear wax of a person with ochronosis will also be dark in color.

Is ochronosis reversible?

While this has not proven effective in reversing or removing existing ochronotic deposits, it possesses the capability to arrest the deposition process.

How do you reverse exogenous ochronosis?

Hydroquinone-induced exogenous ochronosis is an avoidable dermatosis that is exceedingly difficult to treat. However, some studies show that treatment may be possible with a Q-switched alexandrite (755 nm) laser. Individuals with this disorder are recommended to stop using hydroquinone-containing compounds.

What is exogenous ochronosis?

Exogenous ochronosis (EO) is a cutaneous disorder characterized by blue-black pigmentation resulting as a complication of long-term application of skin-lightening creams containing hydroquinone but may also occur due to topical contact with phenol or resorcinol in dark-skinned individuals.

How do you get rid of ochronosis?

Ochronotic arthropathy is treated with physiotherapy, analgesia, rest, and prosthetic joint replacement when necessary. Exogenous ochronosis caused by topical hydroquinone use has been treated successfully with picosecond laser.

What is the best treatment for ochronosis?

How common is ochronosis?

The incidence of exogenous ochronosis is rare in the United States, with less than 25 reports from 1985 to 2010. This reported incidence suggested one case per 300-450 million units of hydroquinone sold in the U.S. [5].

Can laser treat ochronosis?

Conclusion: The QS alexandrite laser can effectively treat exogenous ochronosis without untoward side effects.

Is ochronosis permanent?

This activity reviews the two types of ochronosis, a permanent discoloration caused by the deposition of phenols into connective tissue, and highlights the management of the interprofessional team in treating this condition.