What does Korlym treat?
Korlym® (mifepristone) is a cortisol receptor blocker indicated to control hyperglycemia secondary to hypercortisolism in adult patients with endogenous Cushing’s syndrome who have type 2 diabetes mellitus or glucose intolerance and have failed surgery or are not candidates for surgery.
How do I use Korlym?
Take this medication by mouth with a meal as directed by your doctor, usually once daily. Swallow the tablets whole. Do not crush, chew, or split the tablets. The dosage is based on your medical condition, response to treatment, and other medications you may be taking.
Is Korlym the same as mifepristone?
Pregnancy must also be excluded if treatment is interrupted for more than 14 days in females of reproductive potential. KORLYM (mifepristone) is a cortisol receptor blocker for oral administration. The chemical name of mifepristone is 11ß-(4-dimethylaminophenyl)-17ß-hydroxy-17α-(1-propynyl)-estra-4,9-dien-3-one.
How long does it take for Korlym to work?
60% of patients had a 25% or greater reduction in blood sugar, with improvement seen as early as 6 weeks after initial treatment. A 1.1% reduction in HbA1c was seen by week 24 of treatment.
What are the side effects of Korlym?
The most common side effects of Korlym include:
- Decreased appetite.
- Pain in your arms and legs (arthralgia)
- Swelling of your arms and legs. (peripheral edema)
Is there a generic for Korlym?
mifepristone tablet;oral Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Korlym. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy.
How much does Korlym cost?
Dr. Joseph Belanoff, chief executive of the drug’s maker, Corcept, said Korlym’s average cost per patient is $180,000 annually and concedes that “we have an expensive drug.
Can you get pregnant on Korlym?
This form of medication is called mifepristone (Mifeprex) . Is pregnancy allowed while taking Korlym (mifepristone)? Before starting Korlym (mifepristone), women must not be pregnant, and pregnancy isn’t allowed while taking Korlym (mifepristone).
What is the diet for Cushing Syndrome?
Since calcium and vitamin D strengthen bones, doctors recommend a healthy diet rich in calcium and vitamin D for people with Cushing’s. This includes kale, cheese and broccoli, as well as milk and beverages fortified with vitamin D. Multivitamins are also a valuable source of calcium and vitamin D.
Can you lose weight if you have Cushing’s?
Patients with Cushing’s syndrome classically present with centripetal obesity, which is seen in 90% of the cases. Though weight gain is the rule in Cushing’s syndrome, a paradoxical weight loss can be seen in a subgroup of patients, including those with a malignant tumour as the cause of Cushing’s syndrome.
What happens if Cushing’s is left untreated?
Left untreated, Cushing syndrome can result in exaggerated facial roundness, weight gain around the midsection and upper back, thinning of your arms and legs, easy bruising and stretch marks. Cushing syndrome occurs when your body has too much of the hormone cortisol over time.
What are the side effects of korlym?