What is SV40 replication?

Initiation of DNA Replication The Origin-The SV40. origin of replication is a 64-base pair. segment of the viral genome that contains all of the nucleotide sequence elements that are required for initiation of viral DNA replication.

What are the 6 steps of viral replication?

Key Points. Viral replication involves six steps: attachment, penetration, uncoating, replication, assembly, and release. During attachment and penetration, the virus attaches itself to a host cell and injects its genetic material into it.

What are the 4 steps of viral replication?

Entry, the first step of virus infection, involves the recognition of viral receptor by a virus particle. The viral entry can be divided into four steps: attachment, penetration, cytoplasmic trafficking, and uncoating.

Is SV40 a promoter?

The early promoter of the simian virus 40 (SV40) has been used as a model eukaryotic promoter for the study of DNA sequence elements and cellular factors that are involved in transcriptional control and initiation.

What are the two types of viral replication?

There are two processes used by viruses to replicate: the lytic cycle and lysogenic cycle. Some viruses reproduce using both methods, while others only use the lytic cycle. In the lytic cycle, the virus attaches to the host cell and injects its DNA.

Who discovered SV40?

SV40 was first identified by Ben Sweet and Maurice Hilleman in 1960 when they found that between 10-30% of polio vaccines in the USA were contaminated with SV40. In 1962, Bernice Eddy described the SV40 oncogenic function inducing sarcoma and ependymomas in hamsters inoculated with monkeys cells infected with SV40.

What is Virus Replication called?

No matter the shape, all viruses consist of genetic material (DNA or RNA) and have an outer protein shell, known as a capsid. There are two processes used by viruses to replicate: the lytic cycle and lysogenic cycle. Some viruses reproduce using both methods, while others only use the lytic cycle.