What is the side product of synthesis of aspirin?
One of the esters, acetylsalicylic acid, is aspirin, the common analgesic. We will synthesize aspirin by mixing salicylic acid with acetic anhydride. The second ester product is oil of wintergreen, or methyl salicylate, which we prepare by allowing salicylic acid to react with methanol.
What byproduct is synthesized along with aspirin in the reaction?
Aspirin is synthesized in the lab by performing the acetylation of salicylic acid. For acetylation, acetic anhydride is used.
Is the synthesis of aspirin exothermic or endothermic?
exothermic reaction
In a reaction vessel salicylic acid, acetic anhydride and sulfuric acid are mixed. The exothermic reaction will cause the temperature to increase to 70-80°C. Once the reaction is complete the vessel is cooled in an ice bath and the acetylsalicylic crystallizes out.
Is the synthesis of aspirin an esterification reaction?
The synthesis of aspirin is a simple esterification reaction. When salicylic acid is reacted with acetic anhydride (an acid derivative), the hydroxyl group of this salicylic acid is converted into an acetyl group.
Which of the following is chemical form of aspirin?
Acetylsalicylic acid
Aspirin Chemical Formula
| Chemical Formula of Aspirin (Acetylsalicylic acid) | C9H8O4 |
|---|---|
| Extended Molecular Formula of Aspirin | CH3COOC6H4COOH |
How is aspirin prepared from salicylic acid?
To prepare aspirin, salicylic acid is reacted with an excess of acetic anhydride. A small amount of a strong acid is used as a catalyst which speeds up the reaction. In this experiment, sulfuric acid will be used as the catalyst. The excess acetic anhydride will be quenched (reacted) with the addition of water.
Is aspirin synthesis a reversible reaction?
The reaction involves the conversion of a phenol to an ester. This reaction is reversible, which is why aspirin commonly smells of vinegar, as the ASA hydrolyzes in air back to SA and acetic acid.
Is the Wintergreen reaction endothermic?
Be careful the reaction is exothermic.
What are the products of esterification reaction?
Esterification is the chemical process that combines alcohol (ROH) and an organic acid (RCOOH) to form an ester (RCOOR) and water. This chemical reaction results in forming at least one product of ester through an esterification reaction between a carboxylic acid and an alcohol.