Why is captopril used for CHF?
Captopril works by blocking a substance in the body that causes blood vessels to tighten. As a result, the blood vessels relax. This lowers blood pressure and increases the supply of blood and oxygen to the heart. Captopril is also used to help treat heart failure.
Is captopril used for heart failure?
4 Captopril is therefore an effective vasodilator for the treatment of congestive heart failure. In patients with intact left ventricular function captopril should not be given because severe hypotensive episodes may occur.
Which ACE inhibitor is best for CHF?
When considering factors such as increased ejection fraction, stroke volume, and decreasing mean arterial pressure, our results suggest that enalapril was the most effective ACE inhibitor.
Are ACE inhibitors used to treat congestive heart failure?
Angiotensin Converting Enzyme (ACE) Inhibitors are a important class of drugs used in the management of Congestive Heart Failure (CHF). They have been shown to decrease mortality in patients with left ventricular systolic dysfunction or exhibit congestive heart failure after an infarction.
When should I take captopril sublingual?
Given by mouth, captopril is usually effective within 15-30 minutes and may be repeated in 1-2 hours depending upon the response. The drug has been administered sublingually, in which case the onset of action may occur within 10-20 minutes, with the maximal effect reached within 1 hour.
When should you not use captopril?
 If a marked elevation of hepatic transaminases or jaundice occurs, captopril should be discontinued. A persistent, dry, hacking, nonproductive cough that occurs within the first few months of treatment can also occur with captopril therapy.
Who should not take captopril?
You should not use this medicine if you are allergic to captopril or to any other ACE inhibitor, such as benazepril, fosinopril, enalapril, lisinopril, moexipril, perindopril, quinapril, ramipril, or trandolapril. You may also need to avoid taking captopril with aliskiren if you have kidney disease.
What is the first line treatment for congestive heart failure?
Loop diuretics should be used as first-line agents, with thiazides added for refractory fluid overload. Diuretic treatment should be combined with a low-salt diet,8 a β-blocker, and an ACE inhibitor. The practitioner should begin with oral furosemide, 20 to 40 mg once daily.
Is captopril an emergency medicine?
There is a paucity of data regarding the use of Captopril in hypertensive urgency within African emergency centres. A dose of 25 mg of captopril appears to be effective in managing hypertensive urgency and to control the blood pressure.
What should I check before giving captopril?
Your blood pressure will need to be checked often, and you may need frequent blood tests. Drink plenty of water each day while you are taking captopril. This medication can cause false results with certain medical tests. Tell any doctor who treats you that you are using captopril.