What is the sensitivity of a QuantiFERON gold test?

The sensitivity of QuantiFERON-TB Gold is as high as 92% in individuals with active disease, but varies depending on the setting and extent of TB disease (12). Sensitivity is the probability that the test indicates a person has the disease (or infection) when in fact that person does have the disease.

Is QuantiFERON gold specific?

QFT-Plus is a highly accurate test with >97% specificity for detection of TB infection.

How accurate is QFT test?

The overall sensitivity for active TB was 87.5%, ranging from 62.5% in children 25–36 months old to 100% in children older than 49 months. The overall specificity for active TB was 93.6%.

What does indeterminate mean on QuantiFERON gold?

An indeterminate test result in QFT-G In-Tube test indicates that the real disease status of the person could not be ascertained. An indeterminate result is meaningful and it does not indicate a failed test.

What does high mitogen nil mean?

An extremely high Nil may indicate a problem with specimen handling, while an extremely low Mitogen-Nil level can be seen in immunosuppressed and severely lymphopenic patients. Consideration of these values may be of interpretive value in the event of an Indeterminate result.

Which is better QuantiFERON or T-spot?

In summary, T-SPOT. TB showed higher overall sensitivity than QFT-GIT (91.0% vs. 80.2%). Both QFT-GIT and T-SPOT.

What does high Mitogen nil mean?

Should QuantiFERON gold test be done yearly?

Annual Screening, Testing, and Education Annual TB testing of health care personnel is not recommended unless there is a known exposure or ongoing transmission at a healthcare facility. Health care personnel with untreated latent TB infection should receive an annual TB symptom screen.

Does BCG vaccine cause positive QuantiFERON gold test?

Results: Among 100 adults who were BCG-vaccinated and had a positive TST result, 30 (30%) had a positive result using QFT-G. Persons from high-incidence countries were 8.2 times more likely to have a positive QFT-G result compared with persons from low-incidence countries (46% versus 9%).

Is QuantiFERON gold better than PPD?

The QuantiFERON (QFT) blood assay tests for tuberculosis. Patients must get their blood drawn for a QuantiFERON exam. However, QFT candidates receive exam results in 48-72 hours. Compared to PPD wait times, QuantiFERON provides a sizeable advantage.

What is a normal Mitogen nil level?

Mitogen-Nil The maximum non-specific stimulated interferon- gamma level that may be produced by the patient’s lymphocytes minus the Nil (i.e., basal) level of interferon-gamma. (The reporting range for the Nil is 0 – >8.0. The reporting range for the Tb Antigen-Nil and Mitogen-Nil is 0 – >10 IU/mL.)